Well, I'm not what you would call an "ackump-lishd mew-zishun" by any means but I do play pretty (creatively) mean drums, most sorts of percussion - including tuned - and dustbins and plastic water dispensing bottles.... (obviously I prefer to hit things cos if I didn't I'd probably end up hitting lots of people instead).......plus a dabbler (note cruciality of this term) on keyboards, accordian, melodica, synth, sound generators, samplers.....
Never practised piano good enough to play properly but cannot read music anyway - so the few tunes I DO know how to play are all played by ear (I can pick out chords this way pretty well).
Likewise I cannot play guitar but am sort of capable of playing simple things like, say, Pixies / Kim Deal bass lines (or even Hooky ones) in a one-note-at-a-time capacity.....
However, I'm a dab hand at playing ALL instruments and creating Krautrock-esque symphonies, by virtue of the fact than I'm a devil when it comes to one-chord guitar mantras and such like. But yeah - I wish I COULD play guitar - only problem is, my short attention span means it's impossible for me to even be devoted enough to put aside endless hours every day practising properly and learning how to figure it all out.....my own loss I guess.... :(
I'm also pretty adroit at just making "computer-generated noise" for example....working with loops, samples and found noises or simply beats/sounds nicked off other records......it's just it takes me absolutely ages to play the instruments "virtually" and then sequence every thing together to produce something resembling a piece of music.....